imidazo[1,2-a]pyridine-3-carboxylic acid, 2-methyl-

imidazo[1,2-a]pyridine-3-carboxylic acid, 2-methyl- - Names and Identifiers

Name	2-methylimidazo[1,2-a]pyridine-3-carboxylic acid
Synonyms	BUTTPARK 95-56 ASISCHEM C71528 3-Carboxy-2-methylimidazo[1,2-a]pyridine 2-methylimidazo[1,2-a]pyridine-3-carboxylate 2-a)pyridine-3-carboxylicacid,2-methyl-imidazo( 2-methylimidazo[1,2-a]pyridine-3-carboxylic acid 2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID imidazo[1,2-a]pyridine-3-carboxylic acid, 2-methyl- IMidazo[1,2-a]pyridine-3-carboxylic acid, 2-Methyl-
CAS	21801-79-6
InChI	InChI=1/C9H8N2O2/c1-6-8(9(12)13)11-5-3-2-4-7(11)10-6/h2-5H,1H3,(H,12,13)

imidazo[1,2-a]pyridine-3-carboxylic acid, 2-methyl- - Physico-chemical Properties

Molecular Formula	C9H8N2O2
Molar Mass	176.17
Density	1.35±0.1 g/cm3(Predicted)
Melting Point	140 °C
Boling Point	170°C
pKa	-0.55±0.41(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.653

imidazo[1,2-a]pyridine-3-carboxylic acid, 2-methyl- - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust.
HS Code	29339900
Hazard Class	IRRITANT

imidazo[1,2-a]pyridine-3-carboxylic acid, 2-methyl- - Introduction

2-methyllimidazo [1,2-a]pyridine-3-carboxylic acid is an organic compound with the chemical formula C8H7N3O2.

Nature:
-Appearance: 2-methyllimidazo [1,2-a]pyridine-3-carboxylic acid is a white to yellowish crystalline powder.
-Melting point: About 215-219 ℃.
-Solubility: insoluble in water, but soluble in organic solvents such as ethanol, methanol and dichloromethane.

Use:
2-methyllimidazo [1,2-a]pyridine-3-carboxylic acid is an important intermediate, which is widely used in organic chemical synthesis. It can be used to prepare various imidazo [1,2-a] pyridine compounds, such as heterocyclic ketones and fluorine-containing compounds.

Method:
According to literature reports, 2-methyllimidazo [1,2-a]pyridine-3-carboxylic acid can be prepared by various methods. A common synthetic route is to first prepare 2-methylimidazolyne by condensation of imidazolyne with ketone, and then react 2-methylimidazolyne with pyridone to produce the target product.

Safety Information:
For specific safety information about 2-methylimidazo[1,2-a]pyridine-3-carboxylic acid, the safety data form (SDS) of the compound or related literature should be carefully read when using it. Chemical reagents should be used under appropriate operating conditions and must follow relevant safe handling and protective measures. These include wearing protective glasses, gloves, and appropriate respiratory protection equipment, while operating in a well-ventilated area. Any contact with the compound, such as skin or eye contact, should be immediately rinsed with plenty of water and seek medical assistance.

Last Update：2024-04-10 22:29:15